2006년 10월 20일
유전자변형 작물은 정말 위험한가?
무시무시한 유전자변형콩.
다른 분들 견해도 한번 들어봅시다. 최신결과 두개만 소개합니다. 결론만 말씀드리자면 유전자변형 작물이나 전통작물이나 큰 차이가 없었다는 이야깁니다. 처음 것은 토끼한테 먹인 다음, 몸안에서 다르게 대사가 되는가를 본 것이고 두번째 것은 사람에게 알러지를 다른 식으로 일으키는 것인가를 본 것인데, 두 결과 모두 유전자변형 작물이 전통작물과 크게 다른 반응을 보이지 않았다는 이야깁니다.
Genetically modified soya bean in rabbit feeding: detection of DNA fragments and evaluation of metabolic effects by enzymatic analysis. Animal Science (2006), 82(2), 193-199.
The presence of DNA fragments in tissues from rabbits given genetically modified (GM) soya-bean meal (solvent extd.) was investigated by using the polymerase chain reaction (PCR) approach. Moreover, the possible effects on cell metab. were evaluated by detn. of several specific enzymes in serum, heart, skeletal muscle, liver and kidney. The chloroplast sequence for tRNA Leu by using the Clor1/Clor2 primers designed on chloroplast trnL sequence was clearly detected. On the contrary, two couples of species specific primers for conventional (Le1-5/Le 1-3 which amplifies the soya bean lectin gene) and genetically modified (35S1/35S2 which amplifies the 35S CMV promoter that is present in the genomic structure of GM soya bean) soya bean were not found in all samples. No differences in enzyme levels were detected in serum, but a significant increase of lactic dehydrogenase, mainly concerning the LDH1 isoenzyme was found in particular in kidney and heart but not in the muscle, thus suggesting a potential alteration in the local prodn. of the enzyme. Finally, no significant differences were detected concerning body wt., fresh organ wts. and no sexual differences were detected.
Lack of detectable allergenicity of transgenic maize and soya samples. Journal of Allergy and Clinical Immunology (2005), 116(2), 403-410.
Background: The safety issues regarding foods derived from genetically modified (GM) plants are central to their acceptance into the food supply. The potential allergenicity of proteins newly introduced in GM foods is a major safety concern. Objective: We sought to monitor, in potentially sensitive human populations, the allergenicity effects of 5 GM materials obtained from sources with no allergenic potential and already under commercialization in the European Union. Methods: We have performed skin prick tests with protein exts. prepd. from transgenic maize (MON810, Bt11, T25, Bt176) and soya (Roundup Ready) samples and from nontransgenic control samples in 2 sensitive groups: children with food and inhalant allergy and individuals with asthma-rhinitis. We have also tested IgE immunoblot reactivity of sera from patients with food allergy to soya (Roundup Ready) and maize (MON810, Bt11, Bt176) samples, as well as to the pure transgenic proteins (CryIA[b] and CP4 5-enolpyruvylshikimate-3-phosphate synthase). Results: None of the individuals undergoing tests reacted differentially to the transgenic and nontransgenic samples under study. None of the volunteers tested presented detectable IgE antibodies against pure transgenic proteins. Conclusion: The transgenic products under testing seem to be safe in terms of allergenic potential. We propose postmarket testing as an important screening strategy for putative allergic sensitization to proteins introduced in transgenic plants.
다른 분들 견해도 한번 들어봅시다. 최신결과 두개만 소개합니다. 결론만 말씀드리자면 유전자변형 작물이나 전통작물이나 큰 차이가 없었다는 이야깁니다. 처음 것은 토끼한테 먹인 다음, 몸안에서 다르게 대사가 되는가를 본 것이고 두번째 것은 사람에게 알러지를 다른 식으로 일으키는 것인가를 본 것인데, 두 결과 모두 유전자변형 작물이 전통작물과 크게 다른 반응을 보이지 않았다는 이야깁니다.
Genetically modified soya bean in rabbit feeding: detection of DNA fragments and evaluation of metabolic effects by enzymatic analysis. Animal Science (2006), 82(2), 193-199.
The presence of DNA fragments in tissues from rabbits given genetically modified (GM) soya-bean meal (solvent extd.) was investigated by using the polymerase chain reaction (PCR) approach. Moreover, the possible effects on cell metab. were evaluated by detn. of several specific enzymes in serum, heart, skeletal muscle, liver and kidney. The chloroplast sequence for tRNA Leu by using the Clor1/Clor2 primers designed on chloroplast trnL sequence was clearly detected. On the contrary, two couples of species specific primers for conventional (Le1-5/Le 1-3 which amplifies the soya bean lectin gene) and genetically modified (35S1/35S2 which amplifies the 35S CMV promoter that is present in the genomic structure of GM soya bean) soya bean were not found in all samples. No differences in enzyme levels were detected in serum, but a significant increase of lactic dehydrogenase, mainly concerning the LDH1 isoenzyme was found in particular in kidney and heart but not in the muscle, thus suggesting a potential alteration in the local prodn. of the enzyme. Finally, no significant differences were detected concerning body wt., fresh organ wts. and no sexual differences were detected.
Lack of detectable allergenicity of transgenic maize and soya samples. Journal of Allergy and Clinical Immunology (2005), 116(2), 403-410.
Background: The safety issues regarding foods derived from genetically modified (GM) plants are central to their acceptance into the food supply. The potential allergenicity of proteins newly introduced in GM foods is a major safety concern. Objective: We sought to monitor, in potentially sensitive human populations, the allergenicity effects of 5 GM materials obtained from sources with no allergenic potential and already under commercialization in the European Union. Methods: We have performed skin prick tests with protein exts. prepd. from transgenic maize (MON810, Bt11, T25, Bt176) and soya (Roundup Ready) samples and from nontransgenic control samples in 2 sensitive groups: children with food and inhalant allergy and individuals with asthma-rhinitis. We have also tested IgE immunoblot reactivity of sera from patients with food allergy to soya (Roundup Ready) and maize (MON810, Bt11, Bt176) samples, as well as to the pure transgenic proteins (CryIA[b] and CP4 5-enolpyruvylshikimate-3-phosphate synthase). Results: None of the individuals undergoing tests reacted differentially to the transgenic and nontransgenic samples under study. None of the volunteers tested presented detectable IgE antibodies against pure transgenic proteins. Conclusion: The transgenic products under testing seem to be safe in terms of allergenic potential. We propose postmarket testing as an important screening strategy for putative allergic sensitization to proteins introduced in transgenic plants.
# by | 2006/10/20 07:16 | 모기불 낚시통신 | 트랙백(1) | 덧글(7)











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제목 : 유전자변형식품
*[http://bric.postech.ac.kr/issue/gmo.html Hot Issue-GMO(유전자변형) "Genetically Modified Organism : GMO"] Brics 정리 페이지. *[http://www.hs.or.kr/h_biotechnologyfoodacsh.htm 생물공학과 식품 - 유전자 변형 식품 - ACSH(미 과학건강협회) 보고서 :::::: HS......more
그리고 대형 다국적종자회사들이 결국 농업을 지배하는 구조가 될 우려가 있지요.(관련해서 포스팅 하나 해볼만 하겠군요.^^)
눌론 사람가지고 하는 실험이 제일 어렵다고 합니다만.